ABSTRACT Background: With the reduction of global forest resources and the intensification of environmental problems, it is particularly important to seek new solutions for forest resource management. This paper proposes a forest resource management system based on blockchain technology to realize data security sharing and traceability of forest ownership. Through drone on-site verification and blockchain technology, management credibility and efficiency are improved and costs are reduced. The system provides innovative solutions in terms of data credibility, cooperation mechanism, intelligent decision-making, sustainable development, etc., and defines the future development direction. Background problems ownership onsite site reduced mechanism decisionmaking, decisionmaking decision making, making decision-making etc etc. direction

ABSTRACT Background: Strain elastography (SE) and shear wave elastography (SWE) have high diagnostic yield for breast lesions, but the optimal parameters remain elusive. Aim: To evaluate the diagnostic yield of SWE and SE for breast lesions by multivariate logistic regression analysis. Material and Methods: A total of 132 patients with 164 breast tumors were enrolled. Breast lesions were classified with the breast imaging reporting and data system (BI-RADS). Maximum (Emax), mean (Emean) and standard deviation (Esd) of elastic modulus, lesion/fat elasticity ratio and elastographic classification were obtained by SWE. Strain ratio (SR) and elastographic score were obtained by SE. A multivariate logistic regression analysis was performed. The diagnostic efficiencies of BI-RADS classification, SWE, SE and their combination were compared plotting ROC curves. Results: There were 110 benign and 54 malignant lesions which had significantly different SWE and SE parameters. The parameters included in the logistic regression were Esd and elastographic classification obtained by SWE and the elastographic score obtained by SE. When combining SWE with SE, Esd, SR and SWE classification were included in the equation. The areas under ROC curves for BI-RADS classification, SWE, SE and their combination were 0.75, 0.88, 0.79 and 0.89, respectively. Conclusions: The diagnostic value of SWE in combination with SE for breast lesions exceeded that of SE or SWE alone. Esd showed a good diagnostic yield when SWE was used alone or combined with SE.

Antecedentes: La elastografía de deformación (SE) y de onda cortante (SWE) son útiles para el diagnóstico de lesiones mamarias, pero falta definir los parámetros óptimos. Objetivo: Evaluar el valor diagnóstico de SE y SWE en lesiones mamarias usando una regresión logística multivariable. Material y Métodos: Ciento treinta y dos pacientes con 164 tumores mamarios fueron evaluados, los que se clasificaron usando el sistema BI-RADS (breast imaging reporting and data system). El módulo elástico máximo, promedio y su desviación estándar (Esd), la razón entre la elasticidad de la lesión y de la grasa y la clasificación elastográfica se obtuvieron con SWE. La razón de deformación (SR) y el puntaje elastográfico se obtuvieron con SE. Se efectuó una regresión logística y las eficiencias diagnósticas de la clasificación BI-RADS, SWE and SE y su combinación se compararon usando curvas ROC (receiver operating characteristic curves). Resultados: Ciento diez lesiones fueron benignas y 54 malignas. Estas tenían parámetros SWE y SE significativamente diferentes. En la ecuación de regresión logística, se incluyeron la clasificación elastográfica y el Esd obtenidos por SWE y el puntaje elastográfico obtenido por SE. Cuando se combinó SWE y SE, se incluyeron en la ecuación el Esd, SR y la clasificación por SWE. Las áreas bajo la curva ROC para la clasificación BI-RADS, SWE y SE y la combinación de ambas fueron 0.75, 0.88, 079 y 0.89 respectivamente. Conclusiones: La combinación de SWE y SE tuvo un mejor rendimiento diagnóstico para lesiones mamarias que cada parámetro por separado. Esd tuvo un buen rendimiento diagnóstico cuando se utilizó SWE sola o combinada con SE.

RESUMO CONTEXTO E OBJETIVO: Enzimas dimetilarginina dimetilaminohidrolase (DDAH), codificadas por genes DDAH1 e DDAH2, desempenham papel fundamental na manutenção da função endotelial. Realizamos estudo tipo caso-controle na população chinesa, com três grupos étnicos (han, kazakh e uygur) para investigar sistematicamente a associação entre a variação de genes DDAH1 e DDAH2 e a hipertensão. DESENHO E LOCAL: Estudo tipo caso-controle no Departamento de Medicina Interna e Diagnóstico Genético, Hospital de Tongji, Tongji Medical College, Universidade de Ciência e Tecnologia de Huazhong. MÉTODOS: Este estudo incluiu 1.224 pacientes com hipertensão e 967 indivíduos saudáveis, sem parentesco, como controles. DDAH1 -396 4 N (GCGT) del > ins, rs3087894, rs805304 and rs9267551 foram genotipados usando o ensaio nuclease TaqMan 5'. RESULTADOS: O genótipo G/C de rs3087894 no DDAH1 foi um fator de risco para a hipertensão arterial no grupo kazakh em modelo codominante (G/C versus G/G; OR 1,39; IC 95%: 1,02-1,88; P < 0,05), com o mesmo resultado no modelo dominante (G/C + C/C versus G/G; OR 1,38; IC 95%: 1,03-1,84; P < 0,05). Em contraste, o genótipo C/C de rs3087894 parecia ser um fator de proteção para a hipertensão no grupo uygur no modelo recessivo (C/C versus G/G + G/C; OR 0,62; IC 95%: 0,39-0,97; P < 0,05). Achado semelhante para rs3087894 também foi observado depois de se ajustar a variante à covariante idade. CONCLUSÃO: Os nossos resultados indicaram que o C-alelo de rs3087894 no DDAH1 foi fator de risco para a hipertensão no grupo de kazakh, mas fator de proteção no grupo de uygur.

CONTEXT AND OBJECTIVE: Dimethylarginine dimethylaminohydrolase enzymes (DDAH), which are encoded by the genes DDAH1 and DDAH2, play a fundamental role in maintaining endothelial function. We conducted a case-control study on a Chinese population that included three ethnic groups (Han, Kazakh and Uygur), to systemically investigate associations between variations in the genes DDAH1 and DDAH2 and hypertension. DESIGN AND SETTING: Experimental study at the Department of Internal Medicine and Genetic Diagnosis, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology. METHODS: This case-control study included 1,224 patients with hypertension and 967 healthy unrelated individuals as controls. DDAH1 -396 4N (GCGT) del>ins, rs3087894, rs805304 and rs9267551 were genotyped using the TaqMan 5' nuclease assay. RESULTS: The G/C genotype of rs3087894 in DDAH1 was a risk factor for hypertension in the Kazakh group in the co-dominant model (G/C versus G/G) (OR 1.39; 95% CI: 1.02-1.88; P < 0.05), with the same result in the dominant model (G/C + C/C versus G/G) (OR 1.38; 95% CI: 1.03-1.84; P < 0.05). In contrast, the C/C genotype of rs3087894 seemed to be a protective factor against hypertension in the Uygur group in the recessive model (C/C versus G/G + G/C) (OR 0.62; 95% CI: 0.39- 0.97; P < 0.05). Similar findings for rs3087894 were also observed after adjusting the variable for the age covariate. CONCLUSION: Our results indicated that the C-allele of rs3087894 in DDAH1 was a risk factor for hypertension in the Kazakh group but a protective factor in the Uygur group.

For the properties of polymer are relative to its structure, the main purpose of the present work is to investigate the mechanical properties of the aeronautical PMMA which has been treated by the directional tensile technology. Isodyne images reveal the stress state in directional PMMA. And then, an anisotropic mechanical model is established. Furthermore, all mechanical parameters are measured by the digital image correlation method. Finally, based on the anisotropic mechanical model and mechanical parameters, the FEM numerical simulation and experimental methods are applied to analyze the fracture mechanical properties along different directions.